| CAMPSQ196 |
| Title : |
Antibacterial peptide BMAP-27 |
| GenInfo Identifier : |
1708945 |
| Source : |
Bos taurus [Bovine] |
| Taxonomy : |
Animalia, Mammals |
| UniProt: |
P54228 |
| PDB: |
2KET |
| Structure Database : |
CAMPST173 |
| PubMed : |
8910461, 29103679 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
E. coli ATCC25922 ( MIC = 1 microM), E. coli ML35 ( MIC = 1 microM), E.coli D21 ( MIC = 0.25 microM), S. typhimurium ATCC 14028 ( MIC = 1 microM), P. aeruginosa ATCC 27853 ( MIC = 1 microM), S. marcescens ATCC 8100 ( MIC = 2 microM), S. aureus ATCC 25923 ( MIC = 2 microM), S. aureus Cowan 1 ( MIC = 2 microM), S. aureus MRSA ( MIC = 4 microM), S. epidermidis ATCC 12228 ( MIC = 1 microM), B. megaterium Bm11 ( MIC = 2 microM), C.albicans ( MIC = 8 microM), C.neoformans ( MIC = 4 microM) ]Refer PubMed ID: 29103679] S. aureus (LOG 2MIC =5.66),E.coli(LOG 2MIC=3.75) |
| Validated : |
Experimentally validated |
| InterPro : |
IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
|
| AMP Family : |
Cathelicidin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
CathelicidinH27_6 |
HMM |
 |
|
CathelicidinH_140 |
HMM |
|
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IBA |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IBA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IBA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IBA |
| GO:0045087 |
Biological process |
Innate immune response |
IBA |
| GO:0031640 |
Biological process |
Killing of cells of other organism |
IEA |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IBA |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IBA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IBA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IBA |
| GO:0045087 |
Biological process |
Innate immune response |
IBA |
| GO:0031640 |
Biological process |
Killing of cells of another organism |
IEA |
|
| Length : |
27 |
Sequence: |
GRFKRFRKKFKKLFKKLSPVIPLLHLG |
