CAMPSQ110
Title : Magainin 2
GenInfo Identifier : 126683
Source : Xenopus laevis [African clawed frog]
Taxonomy : Animalia, Amphibia
UniProt: P11006
PDB: 1DUM, 2MAG
Structure Database : CAMPST13, CAMPST575
PubMed : 1717472 , 3299384, 35073323
Activity : Antibacterial, Antifungal, Antiparasitic
Gram Nature : Gram +ve, Gram -ve
Target :
[ Refer PubMed : 3299384 :- Escherichia coli D31 ( MIC = 5 microg/ml), Klebsiella pneumoniae ( MIC = 10 microg/ml), Pseudomonas putida ( MIC = 10 microg/ml), Staphylococcus epidermidis ( MIC = 10 microg/ml), Citrobacter freundii ( MIC = 30 microg/ml), Enterobacter cloacae ( MIC = 50 microg/ml), Escherichia coli ( MIC = 50 microg/ml), Staphylococcus aureus ( MIC = 50 microg/ml), Candida albicans ( MIC = 80 microg/ml), Pseudomonas aeruginosa ( MIC = 100 microg/ml), Serratia marcescens ( MIC = 100 microg/ml), Proteus mirabilis ( MIC = >100 microg/ml), Streptococcus fecalis ( MIC = >100 microg/ml)Paramecium caudatum ( MIC = 10 microg/ml), Amoeba proteus , Euglena gracilis ] [ Refer PubMed : 1717472 :- E.coli ATCC 25922 ( MIC = 62-125 microg/ml), Klebsiella Pneumonae ATCC 13883 ( MIC = 125-250 microg/ml), Pseudomonas aeruginosa ATCC 27853 ( MIC = 125-250 microg/ml), Staphylococcus aureus ATCC 29213 ( MIC = >500 microg/ml), Streptococcus faecalis ATCC 29212 ( MIC = >500 microg/ml), Candida ablicansATCC 14053 ( MIC = 250-500 microg/ml) ], [ Refer Pubmed ID 35073323: Mycoplasma pneumoniae ]
Validated : Experimentally validated
AMP Family : Magainin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0050688 Biological process Regulation of defense response to virus IEA
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in another organism IEA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of another organism IDA
GO:0050688 Biological process Regulation of defense response to virus IEA
Length : 23
Sequence:
 GIGKFLHSAKKFGKAFVGEIMNS

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