CAMPSQ1088
Title : Cytoinsectotoxin-1a
GenInfo Identifier : 224471806
Source : Lachesana tarabaevi [Spider]
Taxonomy : Animalia, Arachnida
UniProt: P85253
PubMed : 18215128
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
A. globiformisVKM Ac-1112 ( MIC = 0.5_uM ) , and B.subtilis VKM B-501 ( MIC = 0.9 uM) , E.coli C600 (MIC=0.5 microM), E.coli DH5alpha (MIC=0.9 microM), E.coli MH1 (MIC=0.5 microM), P.aeruginosa PAO1 (MIC=1.9 microM), P.fluorescens VKM B-894 (MIC=3.8 microM)
Hemolytic Activity :
Hemolytic activity against Human erythrocytes ( EC50 = 6 microM ) , Has cytolytic activity against insect Sf9 cells ( EC50 = 1 microM ) , human leukocytes ( EC50 = 3 microM )
Validated : Experimentally validated
Comment : Inactive against M.luteus , S.aureus , S.marcescens
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0090729 Molecular function Toxin activity IEA
GO:0051838 Biological process Cytolysis by host of symbiont cells IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IEA
Length : 69
Sequence:
 GFFGNTWKKIKGKADKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYLLKYYGKK
ALQKASEKL

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