| CAMPSQ1054 |
| Title : |
Fowlicidin-2 , Myeloid antimicrobial peptide 27 |
| GenInfo Identifier : |
123894504, 145579366 |
| Source : |
Gallus gallus [ Chicken] |
| Taxonomy : |
Animalia, Aves |
| UniProt: |
Q2IAL7 |
| PDB: |
2GDL |
| Structure Database : |
CAMPST561 |
| PubMed : |
16326712, 17229147 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
[E. coli ATCC 25922 (MIC = 2.66 microM), E. coli O157:H7 ATCC 700728 (MIC = 0.66 microM), S. typhimurium ATCC 14028 (MIC = 1.33 microM), S. typhimurium DT104 ATCC 700408 (MIC = 0.66 microM), K. pneumoniae ATCC 13883 (MIC = 0.66 microM), P. aeruginosa 27853 (MIC = 5.32 microM), L. monocytogenes ATCC 19115 (MIC = 1.33 microM), S. aureus ATCC 25923 (MIC = 0.66 microM), S. aureus MRSA ATCC BAA-39 (MIC = 0.66 microM), S. aureus MRSA ATCC 43300 (MIC = 0.33 microM)-0mM Nacl] [E. coli ATCC 25922 (MIC = 2.66 microM), E. coli O157:H7 ATCC 700728 (MIC = 1.33 microM), S. typhimurium ATCC 14028 (MIC = 1.33 microM), S. typhimurium DT104 ATCC 700408 (MIC = 1.33 microM), K. pneumoniae ATCC 13883 (MIC = 1.33 microM), P. aeruginosa 27853 (MIC = 2.66 microM), L. monocytogenes ATCC 19115 (MIC = 1.33 microM), S. aureus ATCC 25923 (MIC = 1.33 microM), S. aureus MRSA ATCC BAA-39 (MIC = 1.33 microM), S. aureus MRSA ATCC 43300 (MIC = 2.66 microM)-100mM Nacl] |
| Validated : |
Experimentally validated |
| InterPro : |
IPR001894 : Cathelicidin.
|
| AMP Family : |
Cathelicidin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
CathelicidinH32_2 |
HMM |
 |
|
CathelicidinH_140 |
HMM |
|
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IMP |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0019835 |
Biological process |
Cytolysis |
IMP |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0045087 |
Biological process |
Innate immune response |
IDA |
| GO:0042116 |
Biological process |
Macrophage activation |
IDA |
| GO:0001818 |
Biological process |
Negative regulation of cytokine production |
IDA |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IMP |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0019835 |
Biological process |
Cytolysis |
IMP |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0045087 |
Biological process |
Innate immune response |
IDA |
| GO:0042116 |
Biological process |
Macrophage activation |
IDA |
| GO:0001818 |
Biological process |
Negative regulation of cytokine production |
IDA |
|
| Length : |
32 |
Sequence: |
LVQRGRFGRFLRKIRRFRPKVTITIQGSARFG |
