Clavanin
This family consists of clavanin proteins from the haemocytes of the invertebrate Styela clava (Sea squirt), a solitary tunicate. The family is made up of four alpha-helical antimicrobial peptides, clavanins A, B, C and D. The tunicate peptides resemble magainins in size, primary sequence and antibacterial activity. Synthetic clavanin A displays comparable antimicrobial activity to magainins and cecropins. The presence of alpha-helical antimicrobial peptides in the haemocytes of a urochordate suggests that such peptides are primeval effectors of innate immunity in the vertebrate lineage [PMID: 9001389]. |
The below sequences were used to create Clavanin sequence signatures: |
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ClavaninH23_5, ClavaninH_5, ClavaninP23_5, ClavaninP_5
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CAMPSQ346
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P80710
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3121854
VFQFLGKIIHHVGNFVHGFSHVF
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ClavaninH23_5, ClavaninH_5, ClavaninP23_5, ClavaninP_5
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CAMPSQ347
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O18493
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3121863
VFHLLGKIIHHVGNFVYGFSHVF
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ClavaninH23_5, ClavaninH_5, ClavaninP23_5, ClavaninP_5
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CAMPSQ348
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P80711
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3121864
VFQFLGRIIHHVGNFVHGFSHVF
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ClavaninH23_5, ClavaninH_5, ClavaninP23_5, ClavaninP_5
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CAMPSQ349
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P80713
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3121865
AFKLLGRIIHHVGNFVYGFSHVF
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ClavaninH23_5, ClavaninH_5, ClavaninP23_5, ClavaninP_5
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CAMPSQ572
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O97395
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67460433
FLRFIGSVIHGIGHLVHHIGVAL
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The below sequences were retrieved using Clavanin sequence signatures: |
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ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ346
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P80710
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3121854
VFQFLGKIIHHVGNFVHGFSHVF
|
>
ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ347
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O18493
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3121863
VFHLLGKIIHHVGNFVYGFSHVF
|
>
ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ348
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P80711
|
3121864
VFQFLGRIIHHVGNFVHGFSHVF
|
>
ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ349
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P80713
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3121865
AFKLLGRIIHHVGNFVYGFSHVF
|
>
ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ572
|
O97395
|
67460433
FLRFIGSVIHGIGHLVHHIGVAL
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>
ClavaninH_5, ClavaninH23_5, ClavaninP_5, ClavaninP23_5
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CAMPSQ1816
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O18492
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3121862
LFKLLGKIIHHVGNFVHGFSHVF
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© 2022, Biomedical Informatics Centre, NIRRCH, Mumbai |
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