CAMPSQ332
Title : Dermaseptin-1
GenInfo Identifier : 29337160, 740957
Source : Phyllomedusa sauvagii [Sauvage leaf frog]
Taxonomy : Animalia, Amphibia
UniProt: P24302
PubMed : 9614066 , 1909573
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
Microsporum canis IP 11 94 ( MIC = 50 microg/ml), Tricophyton rubrum IP 1400-82 ( MIC = 100 microg/ml), Arthroderma simii IP 1063-74 ( MIC = 100 microg/ml), Aspergillus fumigatus IP 1025-70 ( MIC = 100 microg/ml), Aerornonas caviae IP 67-16 T ( MIC = 50 microg/ml), Escherichia coli IP 76-24 ( MIC = 5 microg/ml), Nocardia brasiliensis IP 16-80 ( MIC = 200 microg/ml), Cryptococcus neoformans IP 960-67 ( MIC = 15 microg/ml), Cryptococcus neofonnans IP 962-67 ( MIC = 15 microg/ml), Candida albicans IP 884-65 ( MIC = 60 microg/ml)
Validated : Experimentally validated
Pfam : PF12121 : DD_K ( Dermaseptin )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR022731 : Dermaseptin.
AMP Family : Dermaseptin
Signature :
ID Type Pattern / HMM
DermaseptinH34_2 HMM
DermaseptinH_57 HMM
DermaseptinP34_2 Pattern A-L-W-x-T-M-L-K-K-L-G-T-M-A-L-H-A-G-K-A-A-L-G-A-A-A-[DN]-T-I-S-Q-G-T-Q
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of other organism IEA
GO:0050688 Biological process Regulation of defense response to virus IEA
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of another organism IEA
GO:0050688 Biological process Regulation of defense response to virus IEA
Length : 34
Sequence:
 ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India