CAMPSQ191
Title : Defensin-related cryptdin 2 precursor
GenInfo Identifier : 1706339
Source : Mus musculus [Mouse]
Taxonomy : Animalia, Mammals
UniProt: P28309
PubMed : 1500431, 1500163
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
L. monocytogenes, E. coli ML-35p, avirulent S. typhimurium 7953
Validated : Experimentally validated
Comment : Inactive against mouse-virulent S.typhimurium 14028S
Pfam : PF00323 : Defensin_1 ( Mammalian defensin )
PF00879 : Defensin_propep ( Defensin propeptide )
InterPro : IPR016327 : Alpha-defensin.
IPR006080 : Defensin_beta/neutrophil.
IPR002366 : Defensin_propep.
IPR006081 : Mammalian_defensins.
AMP Family : Defensin
Signature :
ID Type Pattern / HMM
DefensinH33_12 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IDA
GO:0042803 Molecular function Protein homodimerization activity ISO
GO:0019731 Biological process Antibacterial humoral response IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0071222 Biological process Cellular response to lipopolysaccharide IGI
GO:0042742 Biological process Defense response to bacterium IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IGI
GO:0050830 Biological process Defense response to Gram-positive bacterium IGI
GO:0002227 Biological process Innate immune response in mucosa IBA
GO:0051673 Biological process Membrane disruption in other organism IBA
GO:0009410 Biological process Response to xenobiotic stimulus IDA
Length : 35
Sequence:
 LRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR

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